Endocrine Abstracts

Introduction: Septo optic dysplasia is a triad of conditions, which include MPHD, IGHD and ONH. We have analysed data in our regional cohort primarily focusing on MRI brain scans.Patients and methods: MRI scans of the brain including T1/T2 weighted high resolution images in children with a diagnosis of septo optic dysplasia (SOD (N=38)), multiple pituitary hormone deficiency (MPHD (N=19)) and isolated GH deficiency (IGHD (n=14)) (tot...

Over the last few years, we have seen increasing numbers of referrals to our regional paediatric endocrine unit with premature sexual maturation (PSM), especially adrenarche and isolated thelarche. Therefore, we audited referrals for PSM over three years, and compared them to published historical data collected over 15 years in another regional paediatric endocrine unit (Bridges et al. 1994).<thead valig...

Introduction: Optic nerve hypoplasia (ONH) can be bilateral or unilateral. It may be found either as an isolated finding or as part of other conditions such as septo-optic dysplasia (SOD), a variable triad of ONH, midline brain defects, and hypopituitarism. We have analysed data on patients with ONH within our regional cohort.Patients and methods: Ophthalmology and endocrinology case records from 136 patients with SOD (56) or ONH (79) were analysed. ONH ...